Melatonin as a raw material for health food

Sleep is closely related to health, but in reality, many people suffer from insomnia. The well-known drugs for treating insomnia include "Anding" and "Letan". In recent years, melatonin has risen rapidly and been promoted by businesses as a "miracle medicine" for treating insomnia. Is melatonin really so magical?

On December 1, 2020, in accordance with the Food Safety Law of the People's Republic of China and the Measures for the Administration of the Catalogue of Health Food Raw Materials and the Catalogue of Health Functions, the State Administration for Market Regulation, in conjunction with the National Health Commission and the State Administration of Traditional Chinese Medicine, formulated a catalog of five health food raw materials, including coenzyme Q10, which will come into effect on March 1, 2021. Melatonin is among them.

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Melatonin is a naturally secreted hormone in the human body, mainly secreted by the pineal gland. It has a wide range of effects and has regulatory effects on the reproductive system, endocrine system, immune system, central nervous system, and many metabolic processes of the body.
The secretion of melatonin has a clear circadian rhythm. The human body secretes melatonin at night and suppresses it in bright daylight. This secretion characteristic helps the body adjust its sleep state and duration.
The secretion of melatonin is also influenced by various factors such as light intensity, light wavelength, light duration, light cycle, electromagnetic field, environmental purification, etc. Even hunger and vigorous exercise can affect the secretion of melatonin.
As age increases, the secretion of melatonin in the human body gradually decreases. The decrease in melatonin in the body of elderly sleep disorder patients is more significant, and more and more elderly people are suffering from painful sleep problems.
Research has shown that melatonin has an ideal hypnotic effect at physiological doses (0.1-0.3 milligrams). In China, melatonin is allowed to be used as a raw material for health food, with its health function limited to improving sleep. The recommended daily dose is 0.1-0.3 milligrams. In most sleep aid drugs, the content of melatonin can reach up to 3 milligrams or even 9 milligrams, far exceeding the physiological requirement, which can make people feel dizzy and dizzy after waking up the next morning. For the general insomnia population, experts do not recommend long-term use of melatonin. Mainly because long-term use of exogenous melatonin may lead to a decrease in self secretion; Excessive use of melatonin can increase the burden on the liver and kidneys.
Melatonin only has a certain auxiliary effect on circadian rhythm disorders and melatonin sensitive sleep disorders, and is not effective for all types of insomnia. For example, insomnia caused by depression may worsen depressive symptoms after taking melatonin. In addition, melatonin has an impact on certain diseases and medications, and caution should be exercised when using it.

For example, people with coagulation disorders, depression, epilepsy, and organ transplantation are particularly not recommended to take melatonin; For patients with cardiovascular and cerebrovascular diseases who take aspirin for a long time, it is not recommended to use melatonin because aspirin and melatonin can interact with each other, affecting their therapeutic effects. In fact, there are many reasons for insomnia. To improve insomnia symptoms, the first step is to develop good lifestyle habits. First, create a comfortable sleeping environment for yourself, and then consider combining multiple physical, psychological, and medication plans for comprehensive treatment.

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2024-04-18

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