01
Pharmacopoeia records
Source:
This product is a dried and mature seed of the leguminous plant Cassia obtusifolia L. or Cassia tora L. Harvest mature fruits in autumn, sun dry them, plant seeds, and remove impurities. Traits:
Decision: Slightly rhombic or short cylindrical in shape, with both ends parallel and inclined, 3-7mm long and 2-4mm wide. The surface is green brown or dark brown, smooth and glossy. One end is relatively flat, the other end is slanted and pointed, with one raised edge on each side of the back and abdomen. There is one slanted symmetrical and lighter colored linear concave line on each side of the edge. Hard in texture and not easily broken. The seed coat is thin, with 2 yellow cotyledons that are folded and overlapping in an "S" shape. Mild qi, slightly bitter taste. Xiaoxiaming: It is a short cylindrical shape, smaller, 3-5mm long, and 2-3mm wide. There are one broad light yellow brown band on each side of the surface edge. Sexual Taste and Meridian tropism Sweet, bitter, salty, slightly cold. Guigan and Large Intestine Meridian Function and Indications:
Clear heat and brighten the eyes, moisten the intestines and relieve constipation. Used for redness and pain, shyness and excessive tears, headache and dizziness, unclear vision, and constipation.
02
Modern pharmacological effects
1. Hypolipidemic effect
The effective part of Cassia seed for lowering blood lipids is the n-butanol part. Compared with the high-fat blood rat model group, the total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels in the serum of the Cassia seed dose group were significantly increased. The levels of TC and TG in the liver were significantly reduced, and the total superoxide dismutase (T-SOD) was significantly increased, indicating that Cassia seed has a certain lipid-lowering function. 2. Hypotensive effect
Research has shown that the anthraquinone glycoside of Cassia seed can significantly reduce the systolic blood pressure of the tail artery in hypertensive rats with two kidneys and one clip, and has a protective effect on the kidneys of hypertensive rats. Cassia seed protein, oligosaccharides, and anthraquinone glycosides can significantly reduce blood pressure in experimental hypertensive rats. 3. Diarrhea effect
Traditional applications have shown that Cassia seed has a laxative and intestinal moisturizing effect, and the active ingredient may be the anthraquinone substances it contains. Anthraquinone substances have the effect of promoting intestinal peristalsis, reducing the absorption of sterols, and enhancing intestinal excretion. Moreover, the abundant polysaccharides and cellulose in Cassia seed have a significant synergistic effect with anthraquinone substances. 4.Mingmu effect
Cassia seed is named after its outstanding visual function. The n-hexane part of Cassia seed has a significant anti photooxidation effect, which can inhibit the deposition of a pyridine retinol (A2E) induced by light in retinal pigment epithelial cells, and is expected to improve macular degeneration in the eyes of the elderly. 5.hepatoprotective effect
The ethanol extract of Cassia seed has antioxidant effects, which can inhibit the CCl4 induced decrease in cytochrome P4502E1 activity, lower liver and mitochondrial malondialdehyde levels, increase liver and mitochondrial glutathione levels, restore the activity of superoxide dismutase, glutathione reductase, and glutathione S-transferase, and have liver protective effects. 03
Modern Applications
According to the medical intelligence data query, there are currently 464 domestic health foods containing cassia seeds, 26 imported health foods, and 74 enterprise standards related to cassia seeds. According to the search results of the efficacy of domestically produced health food from Cassia seed, there are 153 weight loss benefits, 133 auxiliary lipid-lowering and lipid-lowering benefits, 118 bowel movements, 28 relief of visual fatigue, 24 auxiliary blood pressure lowering and blood pressure regulation benefits, and 15 auxiliary protective effects for chemical liver injury. In recent years, due to factors such as the increase in domestic grain purchase prices, the production of domestic cassia seeds has decreased. However, some of China's cassia seeds come from foreign imports, so there has not yet been a supply and demand gap. But in fact, domestically produced cassia seeds have better quality, and their production currently cannot meet market demand. Cassia seed belongs to the category of medicinal and edible homologous substances, with a wide distribution, abundant and easily obtainable resources, simple processing methods, and a long history of application in the folk. It has the functions of clearing heat, brightening eyes, moistening intestines, and promoting bowel movements.
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2024-02-26
Shaanxi Huike Botanical Development Co., Ltd.
