Portulaca oleracea is a familiar medicinal and edible plant, but there is also a plant called "false Portulaca oleracea", which is named because its shape looks very similar to Portulaca oleracea. Bacopa monieri, also known as Water Hyssop, is a perennial creeping plant. Unlike the yellow flowers of Portulaca, the flowers of Bacopa monieri are white to purple in color, and its leaves are relatively small, elliptical in shape. It usually grows in warm and humid places such as freshwater tidal swamps, riverbank areas, streams, ponds, and muddy coasts.
01
The History of False Purslane
Fake purslane was originally described as a Chinese Herbal medicine in literature around the 6th century AD. Fake purslane is also commonly known as Brahmi, named after the Hindu god of creation Brahma. Especially when used in combination with other herbs that claim to enhance intelligence, such as centella asiatica, it is used to improve a range of mental conditions, such as anxiety, poor cognitive ability, and lack of concentration. It is currently sold as a memory enhancing supplement in Western countries. 02
The role of false purslane
Pseudopurslane has various pharmacological effects, including antioxidant, anti-inflammatory, anticonvulsant, cardiotonic, bronchodilator, and peptic ulcer protection. False purslane leaf powder has been proven to have antioxidant properties. (1) A small (17 patient) randomized controlled trial published in 2014 demonstrated the function of pseudopurslane as a cognitive performance enhancer. They noticed that after taking a dose of fake purslane (320 mg and 640 mg), there was a statistically significant improvement in cognitive abilities (mental arithmetic, Stroop, letter search, visual tracking), emotional improvement, and stress induced cortisol response. A stronger improvement effect was observed at a dose of 640 milligrams. (2) According to a study, fake purslane can also help people with mild memory problems. Although in this clinical trial, fake purslane was part of a herbal mixture. However, in another randomized, double-blind, placebo-controlled study, patients (54 adults) received 300 milligrams of standardized pseudo purslane extract or placebo. After a 12 week trial, measurement results were obtained by evaluating tasks related to attention, memory, and psychological state. Compared with placebo, the treatment group showed an enhanced ability to recall delayed words and ignore irrelevant information (Stroop test). Another randomized, double-blind study (81 adults aged 55 and above) reported that a 12 week pseudo purslane cycle significantly improved memory acquisition and retention in healthy elderly Australians. (3) Excitingly, another clinical trial has shown that fake purslane can help patients with Alzheimer's disease (AD). Record the starting data of the Mini Mental State Examination Scale (MMSES) for Alzheimer's disease patients aged 60-65. During the experiment, 300 milligrams of standard extract of fake purslane were orally taken twice a day for 6 months, and the MMSES score was recorded again after the medication was completed. Patients showed statistically significant improvements in various components of MMSES, including time, location, and human direction, attention, and their language components in reading, writing, and comprehension. The patients participating in this trial also reported an improvement in their quality of life, as well as a reduction in irritability and insomnia. (4) In addition to emotional health, purslane has an anti anxiety effect on people with decreased cognitive abilities. The combination of fake purslane and centella asiatica has been shown in double-blind randomized clinical trials to effectively alleviate general anxiety symptoms. Interestingly, in a clinical trial, pseudopurslane was found to be associated with an improvement in pleasure deficiency compared to Celexa antidepressants. On the other hand, when used in combination with other herbs, several studies have shown that herbal mixtures can alleviate symptoms of depression and stress. (5) Other animal studies have shown that false purslane is beneficial for epilepsy, Parkinson's disease, and cerebral ischemia/infarction. It has been proven to improve animal gastric ulcers and has anti Helicobacter pylori activity in human colon tissue.
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The mechanism of action of false purslane
According to reports, the cognitive enhancement properties of pseudopurslane may come from the presence of a group of saponins collectively known as pseudopurslane glycosides and their antioxidant effects. Purified purslane glycosides A and B, as well as purslane alcohol extracts, can promote learning, memory, and cognitive abilities. Based on animal research results, it has been shown that extracts of pseudopurslane and purslane glycosides can enhance the antioxidant status of the hippocampus, frontal cortex, and striatal brain regions, thereby regulating the output of the hypothalamic pituitary adrenal (HPA) axis and protecting the hippocampus. Research has shown multiple mechanisms of action, including acetylcholinesterase inhibition β- Decreased amyloid protein, activation of choline acetyltransferase, increased cerebral blood flow, and enhancement of monoamine. The neuroprotective effect of false purslane has been widely studied. In the diabetes model, it can improve the oxidative stress induced by diabetes. Compared with non diabetes rats, reduced glutathione in diabetes rats was significantly reduced due to oxidative stress. Fake purslane can also increase the level of reduced glutathione. There is also evidence to suggest that long-term exposure to cigarette smoke in the human body increases oxidative stress, while pseudopurslane A, through its antioxidant potential, reduces the formation of free radicals and has been found to prevent smoking induced cerebrovascular diseases. In addition, fake purslane has been proven to support γ- The production of aminobutyric acid (GABA) reduces neuronal excitability, thereby improving rapid response decision-making. GABA is a neurotransmitter that can provide sedative effects to the brain. False purslane has been shown to increase GABA by enhancing GABA A receptor subunits and upregulating glutamate decarboxylase.
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Application of fake purslane products
As mentioned earlier, fake purslane is mainly sold as a memory enhancing product in the European and American markets. For example, Mind Lab Pro contains a variety of plant based supplements that can be used to improve memory and reaction time. This supplement contains: Cytidine Diphosphate Choline, Phosphatidyl Serine, Marine Pine Bark Extract, Pseudopurslane, Hericium erinaceus, L-Tyrosine, L-Theanine, Rhodiola, and B vitamins. In addition, there is a protein stick called XITE that contains fake purslane ingredients. In addition, each protein stick contains 18 grams of protein, 2 grams of sugar, 14 grams of fiber, and monkey head mushrooms. As a product that enhances brain power, there is also a combination formula of PS and fake purslane, as well as a combination of centella asiatica and fake purslane. False purslane and its valuable components isolated from it have been widely studied for their effects on promoting intelligence, antioxidation, and neurodegenerative diseases, and have been supported by a large number of clinical studies. The effect of fake purslane is not at all fake.
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2024-04-19
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